Recent enthusiasm for annually-produced plant based energy sources has led to a great deal of interest in high-oil spring-crops for the High Plains. With the recent development of production contracts by Blue Sun and Progressive Producers for these crops in the region there has been a steady demand for production information and adaptability of existing cultivars. Crops with potential for the region included in this research are canola (Brassica napus), camelina (Camelina sativa) and brown mustard (Brassica juncea). Some testing was initiated in 2004, but this was expanded to a region wide project in 2005 and 2006 to test available cultivars under both irrigated and rainfed conditions. Additional trials evaluating planting methods and date of planting have been undertaken. Cooperative efforts with the New Crops and Processing Technology Group and the USDA-ARS-NCUAR in Peoria, IL provided oil analyses and fatty acid composition. This presentation will summarize oil and yield data from these regional trials and present thoughts as to where these crops fits best in cropping systems. It appears that there are a number of cultivars within each group that may have potential for economical oil production in the region. Camelina has many advantages in the region with better tolerance of flea beetles, better seedling vigor, good direct harvestability and short growing season, but less of the total production practices have been worked out with this crop including weed, disease and insect control and it appears to be more limited in potential yield in the highest yielding locations. Currently, the best weed control packages for no-till production come with glyphosate tolerance that is only available in spring canola. There is great opportunity to develop improved adaptation of cultivars and improved production systems to make regional bio-diesel production a reality.