Winter wheat-ecofallow-corn rotations are common in the central and high plains.  Drought has severely decreased corn yields.  Preliminary research with skip row configurations suggested that they may conserve moisture for later use during  dry years and stabilize corn yields.  Our objective was to determine whether these patterns increase yield compared to current practices. A skip row is a corn row that is not planted; for example, a single-skip row pattern means plant one row and skip the next (P1S1). In 2004 and 2005, trials were conducted in 9 and 12 locations, respectively. Trials were located across Nebraska and at Akron, CO and at Tribune, KS. Three skip row patterns were compared to conventional or solid planted plots (no skips) at three acre populations. In western Nebraska and Kansas, the populations were 10,000, 15,000 and 20,000 plants/a; 15,000, 22,500 and 30,000 plants/a were used in eastern Nebraska, and at Akron, 12,000 and 16,000 plants/a were used. Significant interaction between population and skip row patterns were not observed and population data were combined. The data showed a wide range of skip row effects on yield dependent on location and year. Several parameters such as rainfall, tillage and residue were analyzed but only low yield of solid patterns correlated with yield increase due to skip rows. After analyzing the 21 site-years, a recommendation emerged. When the field history and the prediction is that yield will be less than about 90 bu/a, use a single or double skip row pattern. With these lower yields, skip row patterns will not hurt and may increase yields 25 to 40% especially at yields below 60 bu/a. But, if the yield is expected to be higher, do not use skip row patterns as yield likely will be reduced by as much as 30%.