In order to evaluate the effect in flocculating kaolin particles (clay 45% and silt 55%) of an organic conditioner (OC) at different rates, mineral conditioners (MC) single and combined, the following laboratory experiment was carried out: A weighed sample of Kaolin particles were placed on 100 ml probes with solutions of CARDON DATO (Biopolymer) 50 mg L^-1 (CD50); 3 Cmol(+) Fe⁺³ kg^-1 (Fe3); 3 Cmol(+) Al⁺³ kg^-1 (Al3); 1.5 Cmol(+) Fe⁺³ kg^-1 + 1.5 Cmol(+) Al⁺³ kg^-1 (FeAl3); CD50 + 1.5 Cmol(+) Fe⁺³ kg^-1 (CD50Fe1,5); CD50 + 1.5 Cmol(+) Al⁺³ kg^-1 (CD50Al1,5); and CD50 + 1.5 Cmol(+) Fe⁺³ kg^-1 + 1.5 Cmol(+) Al⁺³ kg^-1 (CD50FeAl3). Distilled water (DW) was used as the control. A factorial or 23 was applied in order to select the conditioner that gave the lowest significant value in the Concentration of Particles in the Suspension (CPS) and highest Flocculated Volume of Particles (FVP). A second experiment was done including the best treatments from the factorial design in comparison to lower rates of CD, 30 mg L^-1 and 10 mg L^-1, and CD 5 mg L^-1 combined with 1.5 mmol(+) Fe⁺³ 100 g^-1 + 1.5 Cmol(+) Al⁺³ kg^-1 (CD5FeAl1,5) to which a completely randomized design was applied. The results reveal that the lowest CPS was obtained with CD50 (50 mg L^-1) and PAM10 (used as a reference product ) and the maximum (FVP) is obtained when CD 50 is combined with iron and aluminum (MC). The lower value of CPS maybe due to the medium-high charge density and also to the high molecular weight of both polymers and their interaction with the clay particles. In the other hand, the higher flocculated volume can be explained because of the swelling capacity of the moist mucilage and also to the formation of a more open structure favoring the higher permeability and aeration of the kaolin substratum.