Field experiments were conducted to evaluate 46 herbs as potential high-value crops for the ecological conditions of Mississippi.  Annual, biennial, and perennial herbs were grown at four locations (Beaumont, Crystal Springs, Stoneville, and Verona MS), in USDA Hardiness Zones 7 and 8, with soil types ranging from sandy loam to clay loam.  All herbs were transplanted from greenhouse-grown 2 inch (5cm) plugs in the spring of 2006 on raised beds with black plastic mulch and drip tape irrigation.  Crops were fertilized prior to mulching according to soil tests and received weekly fertilizers via the drip lines through mid-summer.   Herbs were harvested at different times, when they reached technical maturity.  Fresh and dry weights of desired plant parts (roots, whole shoots, flowers, leaves, and or stems) were determined.  Active compounds and oil concentrations in dried samples are being determined.  Many herb species grew and developed well under the ecological conditions of Mississippi.  Examples of these include coriander (Coriandum sativum) for seeds, calendula (Calendula officianalis) for flowers, wormwood (Artemesia absinthium) for shoots, perilla (Perilla frutescens) for shoots, basil (Ocimum basilicum and Ocimum sanctum) for shoots.  Our one-year data suggest that many herbs could be grown as high-value crops in Mississippi.