Land application with center-pivot and side-roll irrigation systems is a common strategy for managing saline-sodic waters derived from Coal Bed Natural Gas (CBNG) production in the Powder River Basin (PRB) of Montana and Wyoming. Various soil and plant impacts resulting from 1 to 4 years of CBNG water applications were examined on 6 (2003) to 8 (2004) study sites representing native range grasslands and seeded grass/alfalfa hayfields. Because soil and plant types, water application rates, and water/soil treatment strategies were variable across study sites, parameters measured from each treated (irrigated) site were compared directly to those from representative control (non-irrigated) sites. Soil chemical and physical parameters including pH, EC, SAR, ESP, texture, bulk density, surface infiltration rate, and Darcy flux were measured at 6 depth intervals to 120 cm. Multiple year applications of CBNG water produced consistent trends of increased soil EC and SAR values at depths to 60 cm, reduced surface infiltration rates, and reduced Darcy flux rates to 120 cm. CBNG water applications increased above-ground plant biomass production and aerial cover. Impacts on plant species richness, frequency, and infectivity rates of arbuscular mycorrhizae (AM) fungi were variable and complex, reflecting site specific conditions and management.