A two year study aiming to examine (1) the optimum seeding rate for newer spring wheat (Triticum aestivum L) cultivars under intensive wheat management conditions; (2) the optimum nitrogen (N) rate and timing of N application to maximize yield and quality; and (3) the contribution of main stem versus other tillers to grain yield was conducted in North Dakota. The study was conducted in 2003 and 2004 under dryland conditions at Casselton and under irrigated conditions at Carrington, ND. In 2003, the lower seeding rate (3 million plants per hectare) produced a higher yield compared to the higher seeding rate (4.2 million plants per hectare) at both locations with the Carrington site having a significant yield increase of 182 kg ha-1. However, in 2004, the higher seeding rate produced a higher yield compared to the lower seeding rate at the Casselton site with a significant yield increase of 245 kg ha-1, while seeding rate did not significantly affect grain yield at the Carrington site in 2004. In 2003, N timing affected yield at both locations with the two way N split (50% urea at planting, 50% as 28-0-0 at 5 leaf stage) significantly increasing yield compared to all the N application at planting as broadcast urea. In 2004, the N pre-plant treatment produced significantly higher grain yield at both N levels (140 kg ha-1 and 224 kg ha-1) at the Casselton site, while at the Carrington site, the two way N split produced the highest grain yield at both N levels (168 kg ha-1 and 280 kg ha-1). The data on the contribution of tillers to grain yield demonstrated the primary spike and the main tiller (T1) were most important in contributing to overall grain yield with the T2 and T3 tillers contributing significantly less.